Instrumentation

Thermo Fusion

High resolution mass spectra (up to 500,000) can be obtained using a Thermo Scientific Orbitrap Fusion Tribrid mass spectrometer. Sample introduction may be accomplished via direct infusion or by a Thermo Scientific Vanquish Neo nano-UHPLC system. Modes of fragmentation include CID/HCD/ETD. Data generated in any of the Thermo mass spectrometers present in the center can be analyzed in a dedicated processing computer that includes Proteome and Compound Discoverer.

Thermo Exploris 120

High resolution mass spectra (up to 120,000) can be obtained using a Thermo Scientific Orbitrap Exploris 120 mass spectrometer. Sample introduction may be accomplished via direct infusion or by a Thermo Scientific Vanquish UHPLC system. Data generated in any of the Thermo mass spectrometers present in the center can be analyzed in a dedicated processing computer that includes Proteome and Compound Discoverer.

Waters Synapt G2-S HDMS

High resolution mass spectra (over 40,000) can be obtained in concert with gas-phase ion mobility separations. Sample introduction may be accomplished via direct infusion or by a Waters nanoACQUITY UPLC system. Data generated in any of the Waters mass spectrometers present in the center can be analyzed in a dedicated processing computer that includes Protein Global Lynx Server (PLGS) intended for bottom-up protein analysis.

Thermo Q Exactive Focus

High resolution mass spectra (up to 70,000) can be obtained using a Thermo Scientific Orbitrap Q Exactive Focus mass spectrometer. Sample introduction may be accomplished via direct infusion or by a Thermo Scientific UltiMate 3000 UHPLC system. Data generated in any of the Thermo mass spectrometers present in the center can be analyzed in a dedicated processing computer that includes Proteome and Compound Discoverer.

Waters Xevo TQ-S

Unit resolution MS and MS/MS spectra can be obtained using a Waters Xevo TQ-S tandem quadrupole mass spectrometer. Sample introduction may be accomplished via direct infusion or by a Waters ACQUITY UPLC system.

Agilent 6420

Unit resolution MS and MS/MS spectra can be obtained using an Agilent Technologies 6420 Triple Quad mass spectrometer. Sample introduction may be accomplished via direct infusion or by an Agilent Technologies1260 Infinity HPLC system.

Thermo TSQ Evo 8000

Unit resolution MS and MS/MS spectra can be obtained using a Thermo Scientific TSQ Evo 8000 mass spectrometer. Sample introduction may be accomplished via a Thermo Scientific TriPlus RSH autosampler or a Markes International ULTRA-xr/UNITY-xr autosampler/thermal desorption unit. Samples can be separated after sampling on a Thermo Scientific Trace 1310 gas chromatography system.

Thermo ISQ 7000

Unit resolution MS spectra can be obtained using a Thermo Scientific ISQ 7000 mass spectrometer. Sample introduction may be accomplished via a Thermo Scientific AI 1310 autosampler.  Samples can be separated after sampling on a Thermo Scientific Trace 1310 gas chromatography system.

Agilent 7900

Metal analysis can be accomplished using a 7900 Agilent Technologies ICP-MS. Sample introduction may be accomplished via an Agilent Technologies ASX-500 Series autosampler.